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DMT-dI-CE Phosphoramidite Nucleotides for Diagnostics " Molecular Therapy Nucleic Acids

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Description

" Molecular Therapy Nucleic Acids 27 (2022): 854-869

1 (2013): 50-61

"Chemical modification of uridine modulates mRNA-mediated proinflammatory and antiviral response in primary human macrophages

} 5-Me-DMT-2'-O-MOE-C(Bz)-CE-Phosphoramidite is a 2'-MOE phosphoramidite monomer used for solid-phase oligonucleotide synthesis

enabling highly sensitive detection such as hybridization probes and qPCR primers

DMT-dI-CE Phosphoramidite Nucleotides for Diagnostics " Molecular Therapy Nucleic AcidsDMT dI CE Phosphoramidite is a DNA phosphoramidite monomer used for solid phase oligonucleotide synthesis. It contains a deoxyinosine (dI), a 5 dimethoxytrityl (DMT) protecting group for 5 hydroxyl protection, and a cyanoethyl (CE) protecting group on phosphite. dI serves as a universal base that can pair with dA, dC, or dT in DNA duplexes through wobble base pairing. Applications Degenerate and universal primers Wobble base pairing of dI makes it

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